Research Institute of Intelligent Complex Systems 简称IICS
time:2021-03-10 view:10


Qiang LUO   Research Fellow   PhD Supervisor


Director, Centre for Computational System Psychiatry

Shanghai Outstanding Academic Leader (2023)

Clare Hall Visiting Fellow, University of Cambridge (2018-2019)

Clare Hall Life Member, University of Cambridge (2019-)

Senior Visiting Lecturer, King’s College London (2016-2019)

School of Life Sciences, Fudan University (2015-2018)

Institute of Science and Technology for Brain-Inspired Intelligence (ISTBI), Fudan University (2018-2026)

  Research Institute of Intelligent Complex Systems, Fudan University(2026-)

Brief Introduction

Qiang Luo works at the interdisciplinary frontier of complex systems science and brain science, focusing on developing new methods for analyzing complex, multidimensional brain-science data and on their application to adolescent brain development and mental health. He is the principal investigator of the National Key Research and Development Program of China and 5 grants from the National Natural Science Foundation of China, as well as other research grants. He has published over 80 academic papers, including work as first or corresponding author in leading journals such as Nature Mental Health, Science Advances, Nature Communications, JAMA Psychiatry, etc. He currently serves as an editorial board member of authoritative international journals, including Psychological Medicine, and has been invited to write commentaries for top journals such as JAMA Psychiatry. His research has been featured in a Nature Spotlight and recognized with awards including the EU Human Brain Project Diversity in Research Paper Award, the First Prize of the Chinese Medical Science and Technology Award from the Chinese Medical Association, etc.

Education

  • Sep 2008-Sep 2009: Joint PhD, Department of Statistics, University of Oxford, UK

  • Sep 2004-Jun 2010: PhD, Department of Mathematics and Systems Science, National University of Defense Technology

  • Sep 2000-Jun 2004: BSc, Department of Applied Mathematics, National University of Defense Technology

Research Directions

Computational systems psychiatry at the interdisciplinary frontier of complex systems science and brain science

  1. Neural computational mechanisms of social-affective interaction and depression

  2. Modeling of executive function and its relevance to ADHD and ASD

  3. Digital brain models and virtual interventions

Achievement

  1. Luo, Q.*, Robbins, T.W. Multiscale Computation in Psychoradiology for Developmental Psychiatric Disorders: A Conceptual Framework, Psychoradiology, 2026, kkag032.

  2. Luo Q*,Du C,Yu Y G,et al. Interdisciplinary science of complex neural systems: the interdisciplinary frontier of systems science and brain science (in Chinese)[J]. Sci Sin Vitae,2026, 56: 685-694. https://doi.org/10.1360/SSV-2025-0160

  3. Hou, W, Zhu, D, Sahakian, B J, et al., Luo, Q*. Cortical thinning and hippocampal expansion as brain signatures of attention deficit hyperactivity disorder symptom trajectories[J]. Nature Mental Health, 2026, 4: 263-278.

  4. Lu, H, Yan, X Q, et al., Luo, Q*. Deep Learning Reveals a Neurocomputational Mechanism Predicting Depression Risk in Adolescents[J]. Science Advances, 2026, 12(32), eaed0772.

  5. Lu, H, et al., Luo, Q*. Genetic risk-dependent brain markers of resilience: interactions between childhood abuse, genetic risks and brain function[J]. Nature Communications, 2025, 16: 6219.

  6. Li, Q+, Cao, M+, et al., Luo, Q*, for the IMAGEN Consortium. Cognitive predictors of mental health trajectories are mediated by inferior frontal and occipital development during adolescence[J]. Molecular Psychiatry, 2025, 30: 3055-3068.

  7. Hou, W, Sahakian, B J, Langley, C, Yang, Y, Bethlehem, R A I, Luo, Q*. Emotion dysregulation and right pars orbitalis constitute a neuropsychological pathway to attention deficit hyperactivity disorder[J]. Nature Mental Health, 2024, 2: 840-852.

  8. Lu, H, Zhuang, X, Luo, Q*. A brain-inspired way of reducing the network complexity via concept-regularized coding for emotion recognition[C]//Proceedings of the 38th AAAI Conference on Artificial Intelligence. Vancouver: AAAI Press, 2024: 20-27.

  9. Luo, Q+, Kanen, J W+, et al., Robbins, T W. Comparable effects of serotonin in rats and humans on computations underlying flexible decision-making[J]. Neuropsychopharmacology, 2024, 49: 600-608.

  10. Du, X, Yan, Y, Yu, J, Zhu, T, Huang, C C, Zhang, L, Shan, X, Li, R, Dai, Y, Lv, H, Zhang, X Y, Feng, J, Li, W*, Luo, Q*, Li, F*. SH2B1 tunes hippocampal ERK signaling to influence fluid intelligence in humans and mice[J]. Research, 2023, 6: 0269.

  11. Yang, R, et al., Camerer, C, Montague, R, Luo, Q. Dynamic neural reconfiguration for distinct strategies during competitive social interactions[J]. NeuroImage, 2022, 263: 119585.

  12. Dai, Y+, Zhang, L+, Yu, J+, et al., Luo, Q*, Li, F*. Improved symptoms following bumetanide treatment in children aged 3 to 6 years with autism spectrum disorder: a randomized, double-blind, placebo-controlled trial[J]. Science Bulletin, 2021, 66(15): 1591-1598.

  13. Shen, C+, Luo, Q+,, et al., Li, F, Feng, J, Schumann, G, Sahakian, B J, for the IMAGEN Consortium. Neural correlates of the dual pathway model for attention-deficit/hyperactivity disorder in adolescents[J]. American Journal of Psychiatry, 2020, 177(9): 844-854.

  14. Shen, C+, Luo, Q+,*, Chamberlain, S R+, et al., Robaey, P, Feng, J, Sahakian, B J. What is the link between attention-deficit/hyperactivity disorder and sleep? A multimodal examination of longitudinal relationships and brain structure using large-scale population-based cohorts[J]. Biological Psychiatry, 2020, 88(6): 459-469.

  15. Robert, G+, Luo, Q+, et al., Schumann, G, for the IMAGEN Consortium. Association of gray matter and personality development with increased drunkenness frequency during adolescence[J]. JAMA Psychiatry, 2020, 77(4): 409-419.

  16. Luo, Q+, Zhang, L+, Huang, C C+, et al., Li, F*, Feng, J*, Desrivières, S+, Robbins, T W. Association between Childhood Trauma and Risk for Obesity: A Putative Neurocognitive Developmental Pathway[J]. BMC Medicine, 2020, 18(1): 278.

  17. Luo, Q, et al., Paus, T, Weinberger, D R, Murray, R M, Schumann, G, Feng, J*, for the IMAGEN Consortium. Association of a schizophrenia-risk nonsynonymous variant with putamen volume in adolescents: a voxelwise and genome-wide association study[J]. JAMA Psychiatry, 2019, 76(4): 435-445.

time:2021-03-10 view:10


Qiang LUO   Research Fellow   PhD Supervisor


Director, Centre for Computational System Psychiatry

Shanghai Outstanding Academic Leader (2023)

Clare Hall Visiting Fellow, University of Cambridge (2018-2019)

Clare Hall Life Member, University of Cambridge (2019-)

Senior Visiting Lecturer, King’s College London (2016-2019)

School of Life Sciences, Fudan University (2015-2018)

Institute of Science and Technology for Brain-Inspired Intelligence (ISTBI), Fudan University (2018-2026)

  Research Institute of Intelligent Complex Systems, Fudan University(2026-)

Brief Introduction

Qiang Luo works at the interdisciplinary frontier of complex systems science and brain science, focusing on developing new methods for analyzing complex, multidimensional brain-science data and on their application to adolescent brain development and mental health. He is the principal investigator of the National Key Research and Development Program of China and 5 grants from the National Natural Science Foundation of China, as well as other research grants. He has published over 80 academic papers, including work as first or corresponding author in leading journals such as Nature Mental Health, Science Advances, Nature Communications, JAMA Psychiatry, etc. He currently serves as an editorial board member of authoritative international journals, including Psychological Medicine, and has been invited to write commentaries for top journals such as JAMA Psychiatry. His research has been featured in a Nature Spotlight and recognized with awards including the EU Human Brain Project Diversity in Research Paper Award, the First Prize of the Chinese Medical Science and Technology Award from the Chinese Medical Association, etc.

Education

  • Sep 2008-Sep 2009: Joint PhD, Department of Statistics, University of Oxford, UK

  • Sep 2004-Jun 2010: PhD, Department of Mathematics and Systems Science, National University of Defense Technology

  • Sep 2000-Jun 2004: BSc, Department of Applied Mathematics, National University of Defense Technology

Research Directions

Computational systems psychiatry at the interdisciplinary frontier of complex systems science and brain science

  1. Neural computational mechanisms of social-affective interaction and depression

  2. Modeling of executive function and its relevance to ADHD and ASD

  3. Digital brain models and virtual interventions

Achievement

  1. Luo, Q.*, Robbins, T.W. Multiscale Computation in Psychoradiology for Developmental Psychiatric Disorders: A Conceptual Framework, Psychoradiology, 2026, kkag032.

  2. Luo Q*,Du C,Yu Y G,et al. Interdisciplinary science of complex neural systems: the interdisciplinary frontier of systems science and brain science (in Chinese)[J]. Sci Sin Vitae,2026, 56: 685-694. https://doi.org/10.1360/SSV-2025-0160

  3. Hou, W, Zhu, D, Sahakian, B J, et al., Luo, Q*. Cortical thinning and hippocampal expansion as brain signatures of attention deficit hyperactivity disorder symptom trajectories[J]. Nature Mental Health, 2026, 4: 263-278.

  4. Lu, H, Yan, X Q, et al., Luo, Q*. Deep Learning Reveals a Neurocomputational Mechanism Predicting Depression Risk in Adolescents[J]. Science Advances, 2026, 12(32), eaed0772.

  5. Lu, H, et al., Luo, Q*. Genetic risk-dependent brain markers of resilience: interactions between childhood abuse, genetic risks and brain function[J]. Nature Communications, 2025, 16: 6219.

  6. Li, Q+, Cao, M+, et al., Luo, Q*, for the IMAGEN Consortium. Cognitive predictors of mental health trajectories are mediated by inferior frontal and occipital development during adolescence[J]. Molecular Psychiatry, 2025, 30: 3055-3068.

  7. Hou, W, Sahakian, B J, Langley, C, Yang, Y, Bethlehem, R A I, Luo, Q*. Emotion dysregulation and right pars orbitalis constitute a neuropsychological pathway to attention deficit hyperactivity disorder[J]. Nature Mental Health, 2024, 2: 840-852.

  8. Lu, H, Zhuang, X, Luo, Q*. A brain-inspired way of reducing the network complexity via concept-regularized coding for emotion recognition[C]//Proceedings of the 38th AAAI Conference on Artificial Intelligence. Vancouver: AAAI Press, 2024: 20-27.

  9. Luo, Q+, Kanen, J W+, et al., Robbins, T W. Comparable effects of serotonin in rats and humans on computations underlying flexible decision-making[J]. Neuropsychopharmacology, 2024, 49: 600-608.

  10. Du, X, Yan, Y, Yu, J, Zhu, T, Huang, C C, Zhang, L, Shan, X, Li, R, Dai, Y, Lv, H, Zhang, X Y, Feng, J, Li, W*, Luo, Q*, Li, F*. SH2B1 tunes hippocampal ERK signaling to influence fluid intelligence in humans and mice[J]. Research, 2023, 6: 0269.

  11. Yang, R, et al., Camerer, C, Montague, R, Luo, Q. Dynamic neural reconfiguration for distinct strategies during competitive social interactions[J]. NeuroImage, 2022, 263: 119585.

  12. Dai, Y+, Zhang, L+, Yu, J+, et al., Luo, Q*, Li, F*. Improved symptoms following bumetanide treatment in children aged 3 to 6 years with autism spectrum disorder: a randomized, double-blind, placebo-controlled trial[J]. Science Bulletin, 2021, 66(15): 1591-1598.

  13. Shen, C+, Luo, Q+,, et al., Li, F, Feng, J, Schumann, G, Sahakian, B J, for the IMAGEN Consortium. Neural correlates of the dual pathway model for attention-deficit/hyperactivity disorder in adolescents[J]. American Journal of Psychiatry, 2020, 177(9): 844-854.

  14. Shen, C+, Luo, Q+,*, Chamberlain, S R+, et al., Robaey, P, Feng, J, Sahakian, B J. What is the link between attention-deficit/hyperactivity disorder and sleep? A multimodal examination of longitudinal relationships and brain structure using large-scale population-based cohorts[J]. Biological Psychiatry, 2020, 88(6): 459-469.

  15. Robert, G+, Luo, Q+, et al., Schumann, G, for the IMAGEN Consortium. Association of gray matter and personality development with increased drunkenness frequency during adolescence[J]. JAMA Psychiatry, 2020, 77(4): 409-419.

  16. Luo, Q+, Zhang, L+, Huang, C C+, et al., Li, F*, Feng, J*, Desrivières, S+, Robbins, T W. Association between Childhood Trauma and Risk for Obesity: A Putative Neurocognitive Developmental Pathway[J]. BMC Medicine, 2020, 18(1): 278.

  17. Luo, Q, et al., Paus, T, Weinberger, D R, Murray, R M, Schumann, G, Feng, J*, for the IMAGEN Consortium. Association of a schizophrenia-risk nonsynonymous variant with putamen volume in adolescents: a voxelwise and genome-wide association study[J]. JAMA Psychiatry, 2019, 76(4): 435-445.